When Voltammetry Reaches Nanoseconds

When Aging Reaches CD4+ T-Cells: Phenotypic and Functional Changes

Beyond midlife, the immune system shows aging features and its defensive capability becomes impaired, by a process known as immunosenescence that involves many changes in the innate and adaptive responses. Innate immunity seems to be better preserved globally, while the adaptive immune response exhibits profound age-dependent modifications. Elderly people display a decline in numbers of naïve T...

Hsp90 reaches new heights

Introduction Hsp90 (heat-shock protein 90) is an abundant molecular chaperone, but its function seems to be restricted to the folding of proteins involved in cell signalling, such as transcription factors and protein kinases. This restricted set of ‘clients’ (see Fig. 1) makes Hsp90 an attractive target for cancer therapeutics. As an anti-Hsp90 drug is now in clinical trials, the meeting was re...

Precision in visual working memory reaches a stable plateau when individual item limits are exceeded.

Multiple studies have demonstrated that resolution in working memory (WM) declines as the number of stored items increases. Discrete-resource models predict that this decline should reach a stable plateau at relatively small set sizes because item limits prevent additional information from being encoded into WM at larger set sizes. By contrast, flexible-resource models predict that the monotoni...

Cyclic Voltammetry

Practical Problems in Voltammetry 3: Reference Electrodes for Voltammetry

the reactions of interest occur at the surface of the working electrode. Therefore, we are interested in controlling the potential drop across the interface between the surface of the working electrode and the solution (i.e., the interfacial potential). However, it is impossible to control or measure this interfacial potential without placing another electrode in the solution. Thus, two interfa...